To set the temperature, flip the switch to turn the machine on and then rotate the dial. Each number on the dial represent approximately a 30 degree (Celsius) increase in temperature. When the dial is at One, the oven will be at room temperature.
To apply the vacuum, turn the knob labeled vacuum to the left. You will have to push the oven door in to create a seal and begin to evacuate the chamber. If a good seal is made, the vacuum gauge should move quickly beyond -60 kPa. If it does not, purge the oven and try again. When the pressure is sufficiently low enough, you can close off the vacuum by turning the knob all the way to the left.
When you are done with the oven, it can be opened again by turning the purge knob to the right and allowing the pressure to reach 0.